Uncertainty, phase and oscillatory hippocampal recall

Máté Lengyel, Peter Dayan

Research output: Contribution to Book/Report typesConference contributionpeer-review

Abstract (may include machine translation)

Many neural areas, notably, the hippocampus, show structured, dynamical, population behavior such as coordinated oscillations. It has long been observed that such oscillations provide a substrate for representing analog information in the firing phases of neurons relative to the underlying population rhythm. However, it has become increasingly clear that it is essential for neural populations to represent uncertainty about the information they capture, and the substantial recent work on neural codes for uncertainty has omitted any analysis of oscillatory systems. Here, we observe that, since neurons in an oscillatory network need not only fire once in each cycle (or even at all), uncertainty about the analog quantities each neuron represents by its firing phase might naturally be reported through the degree of concentration of the spikes that it fires. We apply this theory to memory in a model of oscillatory associative recall in hippocampal area CA3. Although it is not well treated in the literature, representing and manipulating uncertainty is fundamental to competent memory; our theory enables us to view CA3 as an effective uncertainty-aware, retrieval system.

Original languageEnglish
Title of host publicationNIPS 2006
Subtitle of host publicationProceedings of the 19th International Conference on Neural Information Processing Systems
EditorsBernhard Scholkopf, John C. Platt, Thomas Hofmann
PublisherMIT Press Journals
Pages833-840
Number of pages8
ISBN (Electronic)0262195682, 9780262195683
ISBN (Print)9780262195683
StatePublished - 2006
Externally publishedYes
Event19th International Conference on Neural Information Processing Systems, NIPS 2006 - Vancouver, Canada
Duration: 4 Dec 20067 Dec 2006

Publication series

NameNIPS 2006: Proceedings of the 19th International Conference on Neural Information Processing Systems

Conference

Conference19th International Conference on Neural Information Processing Systems, NIPS 2006
Country/TerritoryCanada
CityVancouver
Period4/12/067/12/06

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