TY - JOUR
T1 - Pregnancy during COVID-19
T2 - social contact patterns and vaccine coverage of pregnant women from CoMix in 19 European countries
AU - CoMix Europe Working Group
AU - Wong, Kerry L.M.
AU - Gimma, Amy
AU - Paixao, Enny S.
AU - Paolotti, Daniela
AU - Karch, André
AU - Jäger, Veronika
AU - Baruch, Joaquin
AU - Melillo, Tanya
AU - Hudeckova, Henrieta
AU - Rosinska, Magdalena
AU - Niedzwiedzka-Stadnik, Marta
AU - Fischer, Krista
AU - Vorobjov, Sigrid
AU - Sõnajalg, Hanna
AU - Althaus, Christian
AU - Low, Nicola
AU - Reichmuth, Martina
AU - Auranen, Kari
AU - Nurhonen, Markku
AU - Petrović, Goranka
AU - Makaric, Zvjezdana Lovric
AU - Namorado, Sónia
AU - Caetano, Constantino
AU - Santos, Ana João
AU - Röst, Gergely
AU - Oroszi, Beatrix
AU - Karsai, Márton
AU - Fafangel, Mario
AU - Klepac, Petra
AU - Kranjec, Natalija
AU - Vilaplana, Cristina
AU - Casabona, Jordi
AU - Faes, Christel
AU - Beutels, Philippe
AU - Hens, Niel
AU - Jarvis, Christopher I.
AU - Edmunds, W. John
N1 - Publisher Copyright:
© 2022, The Author(s).
PY - 2022/12
Y1 - 2022/12
N2 - Background: Evidence and advice for pregnant women evolved during the COVID-19 pandemic. We studied social contact behaviour and vaccine uptake in pregnant women between March 2020 and September 2021 in 19 European countries. Methods: In each country, repeated online survey data were collected from a panel of nationally-representative participants. We calculated the adjusted mean number of contacts reported with an individual-level generalized additive mixed model, modelled using the negative binomial distribution and a log link function. Mean proportion of people in isolation or quarantine, and vaccination coverage by pregnancy status and gender were calculated using a clustered bootstrap. Findings: We recorded 4,129 observations from 1,041 pregnant women, and 115,359 observations from 29,860 non-pregnant individuals aged 18–49. Pregnant women made slightly fewer contacts (3.6, 95%CI = 3.5–3.7) than non-pregnant women (4.0, 95%CI = 3.9–4.0), driven by fewer work contacts but marginally more contacts in non-essential social settings. Approximately 15–20% pregnant and 5% of non-pregnant individuals reported to be in isolation and quarantine for large parts of the study period. COVID-19 vaccine coverage was higher in pregnant women than in non-pregnant women between January and April 2021. Since May 2021, vaccination in non-pregnant women began to increase and surpassed that in pregnant women. Interpretation: Limited social contact to avoid pathogen exposure during the COVID-19 pandemic has been a challenge to many, especially women going through pregnancy. More recognition of maternal social support desire is needed in the ongoing pandemic. As COVID-19 vaccination continues to remain an important pillar of outbreak response, strategies to promote correct information can provide reassurance and facilitate informed pregnancy vaccine decisions in this vulnerable group.
AB - Background: Evidence and advice for pregnant women evolved during the COVID-19 pandemic. We studied social contact behaviour and vaccine uptake in pregnant women between March 2020 and September 2021 in 19 European countries. Methods: In each country, repeated online survey data were collected from a panel of nationally-representative participants. We calculated the adjusted mean number of contacts reported with an individual-level generalized additive mixed model, modelled using the negative binomial distribution and a log link function. Mean proportion of people in isolation or quarantine, and vaccination coverage by pregnancy status and gender were calculated using a clustered bootstrap. Findings: We recorded 4,129 observations from 1,041 pregnant women, and 115,359 observations from 29,860 non-pregnant individuals aged 18–49. Pregnant women made slightly fewer contacts (3.6, 95%CI = 3.5–3.7) than non-pregnant women (4.0, 95%CI = 3.9–4.0), driven by fewer work contacts but marginally more contacts in non-essential social settings. Approximately 15–20% pregnant and 5% of non-pregnant individuals reported to be in isolation and quarantine for large parts of the study period. COVID-19 vaccine coverage was higher in pregnant women than in non-pregnant women between January and April 2021. Since May 2021, vaccination in non-pregnant women began to increase and surpassed that in pregnant women. Interpretation: Limited social contact to avoid pathogen exposure during the COVID-19 pandemic has been a challenge to many, especially women going through pregnancy. More recognition of maternal social support desire is needed in the ongoing pandemic. As COVID-19 vaccination continues to remain an important pillar of outbreak response, strategies to promote correct information can provide reassurance and facilitate informed pregnancy vaccine decisions in this vulnerable group.
KW - COVID-19
KW - Contact survey
KW - Europe
KW - Lockdowns
KW - Pregnancy
KW - Social contact
UR - http://www.scopus.com/inward/record.url?scp=85139919909&partnerID=8YFLogxK
U2 - 10.1186/s12884-022-05076-1
DO - 10.1186/s12884-022-05076-1
M3 - Article
C2 - 36209078
AN - SCOPUS:85139919909
SN - 1471-2393
VL - 22
JO - BMC Pregnancy and Childbirth
JF - BMC Pregnancy and Childbirth
IS - 1
M1 - 757
ER -