TY - JOUR
T1 - Interaction of pesticides with a β-cyclodextrin derivative studied by reversed-phase thin-layer chromatography and principal component analysis
AU - Cserhati, Tibor
AU - Forgacs, Esther
AU - Darwish, Yassin
AU - Oros, Gyula
AU - Illes, Zoltan
PY - 2002
Y1 - 2002
N2 - The interaction of 18 pesticides with a water-soluble β-cyclodextrin polymer (BCDP) was studied by reversed-phase thin-layer chromatography and principal component analysis (PCA) was employed for the elucidation of the relationship between the relative strength of interaction and the calculated surface parameters of the guest molecules. Except for penconazole the lipophilicity of the pesticides decrease in the presence of BCDP. PCA indicated that apolar surface parameters are highly positively correlated with the strength of interaction. The data indicate that the agrochemical characteristics (adsorption, leakage, decomposition, etc) of complexed pesticide molecules can be different from those of uncomplexed ones resulting in modified efficacy.
AB - The interaction of 18 pesticides with a water-soluble β-cyclodextrin polymer (BCDP) was studied by reversed-phase thin-layer chromatography and principal component analysis (PCA) was employed for the elucidation of the relationship between the relative strength of interaction and the calculated surface parameters of the guest molecules. Except for penconazole the lipophilicity of the pesticides decrease in the presence of BCDP. PCA indicated that apolar surface parameters are highly positively correlated with the strength of interaction. The data indicate that the agrochemical characteristics (adsorption, leakage, decomposition, etc) of complexed pesticide molecules can be different from those of uncomplexed ones resulting in modified efficacy.
KW - Modified lipophilicity
KW - PCA
KW - Pesticides
KW - Water-soluble β-cyclodextrin polymer
UR - http://www.scopus.com/inward/record.url?scp=0038092408&partnerID=8YFLogxK
U2 - 10.1023/A:1016020615251
DO - 10.1023/A:1016020615251
M3 - Article
AN - SCOPUS:0038092408
SN - 0923-0750
VL - 42
SP - 235
EP - 240
JO - Journal of Inclusion Phenomena
JF - Journal of Inclusion Phenomena
IS - 3-4
ER -