TY - JOUR
T1 - Effect of Some Benzonitrile Esters on the K+ Uptake of Wheat Seedlings
T2 - Quantitative Structure-Activity Relationships
AU - Bujtas, C.
AU - Cserhati, Tibor
AU - Cseh, E.
AU - Illés, Zoltán
AU - Szigeti, Zoltán
PY - 1987
Y1 - 1987
N2 - The effect of 15 benzonitrile esters on potassium uptake of excised roots of wheat (Triticum aestivum L. cv. F 481) seedlings was determined. The pI50 values were correlated with the lipophilicity of compounds determined by reversed-phase thin-layer chromatography. Calculations proved that lipophilicity alone did not explain the biological activity of the compounds. After introducing a sterical parameter for the presence of a second ring structure in the molecule, very good correlation was found between the biological activity as dependent, and lipophilicity and sterical parameter as independent variables. Our results suggest that hydrophobic interactions may exert a considerable influence on the biological activity. The presence of a second ring structure in the molecule decreases the effectivity, stressing the importance of sterical parameters.
AB - The effect of 15 benzonitrile esters on potassium uptake of excised roots of wheat (Triticum aestivum L. cv. F 481) seedlings was determined. The pI50 values were correlated with the lipophilicity of compounds determined by reversed-phase thin-layer chromatography. Calculations proved that lipophilicity alone did not explain the biological activity of the compounds. After introducing a sterical parameter for the presence of a second ring structure in the molecule, very good correlation was found between the biological activity as dependent, and lipophilicity and sterical parameter as independent variables. Our results suggest that hydrophobic interactions may exert a considerable influence on the biological activity. The presence of a second ring structure in the molecule decreases the effectivity, stressing the importance of sterical parameters.
UR - https://m2.mtmt.hu/api/publication/1499599
U2 - 10.1016/S0015-3796(87)80074-4
DO - 10.1016/S0015-3796(87)80074-4
M3 - Article
SN - 0015-3796
VL - 182
SP - 465
EP - 471
JO - Biochemie und Physiologie der Pflanzen
JF - Biochemie und Physiologie der Pflanzen
IS - 6
ER -