TY - GEN
T1 - Dendritic spiking accounts for rate and phase coding in a biophysical model of a hippocampal place cell
AU - Huhn, Zsófia
AU - Lengyel, Máté
AU - Orbán, Gergo
AU - Érdi, Péter
PY - 2004
Y1 - 2004
N2 - Hippocampal place cells provide prototypical examples of neurons firing jointly phase and rate coded spike trains. We propose a biophysical mechanism accounting for the generation of place cell firing at the single neuron level. An interplay between external theta-modulated excitation impinging the dendrite and intrinsic dendritic spiking as well as between frequency modulated dendritic spiking and periodic somatic hyperpolarization was a key element of the model. Through these interactions robust phase and rate coded firing emerged in the model place cell, reproducing salient experimentally observed properties of place cell firing.
AB - Hippocampal place cells provide prototypical examples of neurons firing jointly phase and rate coded spike trains. We propose a biophysical mechanism accounting for the generation of place cell firing at the single neuron level. An interplay between external theta-modulated excitation impinging the dendrite and intrinsic dendritic spiking as well as between frequency modulated dendritic spiking and periodic somatic hyperpolarization was a key element of the model. Through these interactions robust phase and rate coded firing emerged in the model place cell, reproducing salient experimentally observed properties of place cell firing.
UR - http://www.scopus.com/inward/record.url?scp=10944220849&partnerID=8YFLogxK
U2 - 10.1109/IJCNN.2004.1381173
DO - 10.1109/IJCNN.2004.1381173
M3 - Conference contribution
AN - SCOPUS:10944220849
SN - 0780383591
T3 - IEEE International Conference on Neural Networks - Conference Proceedings
SP - 3125
EP - 3130
BT - 2004 IEEE International Joint Conference on Neural Networks - Proceedings
T2 - 2004 IEEE International Joint Conference on Neural Networks - Proceedings
Y2 - 25 July 2004 through 29 July 2004
ER -