Chemical Complexity of Food and Implications for Therapeutics

Giulia Menichetti; Albert László Barabási; Joseph Loscalzo

doi:10.1056/NEJMra2413243

Chemical Complexity of Food and Implications for Therapeutics

Giulia Menichetti, Albert László Barabási, Joseph Loscalzo^*

^*Corresponding author for this work

Department of Network and Data Science

Research output: Contribution to journal › Review Article › peer-review

Abstract (may include machine translation)

Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug discovery.

Original language	English
Pages (from-to)	1836-1845
Number of pages	10
Journal	New England Journal of Medicine
Volume	392
Issue number	18
DOIs	https://doi.org/10.1056/NEJMra2413243
State	Published - 7 May 2025

Keywords

Diet/Nutrition
Endocrinology
Gastroenterology

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10.1056/NEJMra2413243

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title = "Chemical Complexity of Food and Implications for Therapeutics",

abstract = "Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug discovery.",

keywords = "Diet/Nutrition, Endocrinology, Gastroenterology",

author = "Giulia Menichetti and Barab{\'a}si, \{Albert L{\'a}szl{\'o}\} and Joseph Loscalzo",

year = "2025",

month = may,

day = "7",

doi = "10.1056/NEJMra2413243",

language = "English",

volume = "392",

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journal = "New England Journal of Medicine",

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T1 - Chemical Complexity of Food and Implications for Therapeutics

AU - Menichetti, Giulia

AU - Barabási, Albert László

AU - Loscalzo, Joseph

PY - 2025/5/7

Y1 - 2025/5/7

N2 - Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug discovery.

AB - Food contains more than 139,000 molecules, which influence nearly half the human proteome. Systematic analysis of food–chemical interactions can potentially advance nutrition science and drug discovery.

KW - Diet/Nutrition

KW - Endocrinology

KW - Gastroenterology

UR - https://www.scopus.com/pages/publications/105004786454

U2 - 10.1056/NEJMra2413243

DO - 10.1056/NEJMra2413243

M3 - Review Article

C2 - 40334158

AN - SCOPUS:105004786454

SN - 0028-4793

VL - 392

SP - 1836

EP - 1845

JO - New England Journal of Medicine

JF - New England Journal of Medicine

IS - 18

ER -

Chemical Complexity of Food and Implications for Therapeutics

Abstract (may include machine translation)

Keywords

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