TY - GEN
T1 - Active dendrites
T2 - 25th Annual Conference on Neural Information Processing Systems 2011, NIPS 2011
AU - Ujfalussy, Balázs B.
AU - Lengyel, Máté
PY - 2011
Y1 - 2011
N2 - Computational analyses of dendritic computations often assume stationary inputs to neurons, ignoring the pulsatile nature of spike-based communication between neurons and the moment-to-moment fluctuations caused by such spiking inputs. Conversely, circuit computations with spiking neurons are usually formalized without regard to the rich nonlinear nature of dendritic processing. Here we address the computational challenge faced by neurons that compute and represent analogue quantities but communicate with digital spikes, and show that reliable computation of even purely linear functions of inputs can require the interplay of strongly nonlinear subunits within the postsynaptic dendritic tree.Our theory predicts a matching of dendritic nonlinearities and synaptic weight distributions to the joint statistics of presynaptic inputs. This approach suggests normative roles for some puzzling forms of nonlinear dendritic dynamics and plasticity.
AB - Computational analyses of dendritic computations often assume stationary inputs to neurons, ignoring the pulsatile nature of spike-based communication between neurons and the moment-to-moment fluctuations caused by such spiking inputs. Conversely, circuit computations with spiking neurons are usually formalized without regard to the rich nonlinear nature of dendritic processing. Here we address the computational challenge faced by neurons that compute and represent analogue quantities but communicate with digital spikes, and show that reliable computation of even purely linear functions of inputs can require the interplay of strongly nonlinear subunits within the postsynaptic dendritic tree.Our theory predicts a matching of dendritic nonlinearities and synaptic weight distributions to the joint statistics of presynaptic inputs. This approach suggests normative roles for some puzzling forms of nonlinear dendritic dynamics and plasticity.
UR - http://www.scopus.com/inward/record.url?scp=85162429262&partnerID=8YFLogxK
M3 - Conference contribution
AN - SCOPUS:85162429262
SN - 9781618395993
T3 - Advances in Neural Information Processing Systems 24: 25th Annual Conference on Neural Information Processing Systems 2011, NIPS 2011
BT - Advances in Neural Information Processing Systems 24
PB - Neural Information Processing Systems
Y2 - 12 December 2011 through 14 December 2011
ER -